For sure, I just get antsy when peer review doesn’t come from from external sources
1 patient, T2 since mid-30s and now 59, had kidney transplant 2017 after end-stage diabetic nephropathy and fucked glucose control since 2019. The successful cells were endoderm stem cells from him cultivated by mice they injected with his PBMCs that they then made diabetic. So not from cadavers (except mouse cadaver i guess), which is the actual new part here. Intrahepatic implant, and cells from unrelated donor failed that were embedded at the same time. His personalised mouse-donor cells worked well enough to take him off insulin 3 months later.
It’s good news, but you’re entirely correct that the article missed the point entirely. Thanks for the crash course in islet cell therapy!
Hm, 5 year old journal, with the editor board, funding and half of the authors all from the Chinese Academy of Sciences, but significant hospital contribution. I remain skeptical of the headline but hopeful of the science.
Looming? Sudan is past the looming stage. When do known verified atrocities reach “current reality” status?
I once looked at a job listing for something with very specialist technical knowledge in specific programming areas, for a Japanese company based in Tokyo (pre-covid so remote wasn’t really a thing yet). Pretty niche stuff and needed at least basic Japanese language skills too, so I assumed it would pay ok - even if it wasn’t good or great in comparison with jobs where i was.
After conversion it worked out to be around USD$40k a year, which is probably just over 1/3 of what it would pay at minimum elsewhere. More like 1/4 or less for Silicon Valley type locations, but the rent for a tiny Tokyo shoebox is about the same price even if food is a cheaper. There was no way I was applying for that.
It isn’t just about a weak yen, it’s much more about hugely underpaying people.
Yes, unfortunately i think you’ve missed a few things.
I think that about covers it
Sadly, the ‘G’ in WCAG is ‘guidelines.’ It doesn’t have teeth; there is no legislation around WCAG.
Used to be true. More and more government agencies are referencing the WCAG as the standard, and The Revised 508 Standards which sets the rules for government bodies directly pins it to WCAG v2.0. WCAG compliance has also been specifically ruled in various Title 3 cases, which sets the precedent.
There is still lots of legal ambiguity around accessibility, but the ADA definitely looks at web accessibility and WCAG when something significant is brought to its attention
Ok! You have the right to do that.
But the US Department of Justice has the right to investigate and fine you up to $75k the first time, if it is determined that you are running a business or organisation in the US that provides public accommodations and you are discriminating against people who have disabilities and you could afford to fix it.
Lots of rights for everyone! It’s so nice.
Not just a defense witness, a former federal prosecutor. A judge had to tell a former federal prosecutor “And then if you don’t like my ruling, you don’t give me side eye and you don’t roll your eyes.” like he was a pouty teenager.
As has medicine and most other technologies. And yet… the question is never asked about the long term threats posed by people who aren’t personally hunting and tracking and foraging.
Exactly, and yet the question is never “is agriculture a long-term threat to humanity?”. It’s always the people with medical issues who are acceptable first choices as society’s sacrificial MacGuffin, long before we question any technology that benefits the person who is “just asking questions”.
It’s like we didn’t already do Social Darwinism the first time. Super frustrating.
Even if we ignored the entire history of the word cripple, it still would be remarkable to not consider hunchback or dwarf as physical descriptions. Given that your next question references video games and then we fall down Godwin’s slippery slope, I’m not convinced you’re honestly engaging with the concept of connotation.
the words only have deragatory meaning to those who have decided they are such.
Yes, and when the people who have to live with the consequences of discrimination tell you that you’re speaking in the same way as those who have discriminated against them, it’s worth considering. Even momentarily.
Have a great day, I’m going to go be a cripple elsewhere now. Nah, just kidding, it will still be my couch. Just not this thread.
If you wanted to emphasise the challenges he dealt with, adjectives for his physical appearance were not a good choice. The challenges he would have dealt with may have included chronic pain, limited mobility and discrimination. You could even have said he suffered from kyphosis. But words which have been frequently intended to be derogatory don’t do much to create a sense of empathy.
could be applied to anyone.
And it’s nice to see disability being normalised, even if that wasn’t your intent.
steinmetz was a hunchback cripple dwarf
I never want to hear anyone say again that “nobody calls someone a ‘cripple’ anymore”. Perhaps consider this somewhat less grotesque alternate phrasing: “Steinmetz was a person who experienced significant and debilitating disability”.
natural selection does not choose whats best overall, just those that can reproduce.
That’s not only an incorrect understanding of natural selection, i’d add that Steinmetz chose not to reproduce. If he hadn’t been the topic of your next sentence, I wouldn’t have felt the need to emphasise his personal agency. Or his existence as a person
Oh cool, it’s time to find out how much of a burden on humanity I am and whether I should have been left to die. Just hypothetically of course, I wouldn’t want anyone to misunderstand. I always enjoy this question with my morning coffee.
Now there’s something I haven’t heard in a million years. Thanks for helping me rediscover it!
A song evaded me for maybe 5 or 6 years once. I ended up having this same conversation about evasive songs with someone and did my best at an impression, because it’s instrumental.
“Doo-d’ Doo Doo, Doodoo Doo, Doo-d’ Doo Doo, Doodoo Doo…”
The person I was talking to instantly said it was Eple - Röyksopp, and was entirely correct.
Covid amplified mine hard-core and was the reason i sought diagnosis. I’ve heard others have experienced similar but I have no idea if this is a widespread thing, and it will be years before research attempts to check. It makes sense though, given the serotonin changes and the way neurotransmitters interact and regulate one another
Which kind? We’ve got bunches. The sulphur crested are the most famous, and they are great but can be vandals
The video in the article has some good footage too. The “why is there bright light when I am nocturnal?!” face is a mood I felt on a deeply personal level.